CalmEze EQ 60ml is a nutritional calming paste developed for horses that become nervous, anxious, excitable or difficult to settle during stressful situations. The easy-to-use oral syringe provides targeted calming support before events such as travelling, competitions, training, changes in environment or other situations that may make a horse tense or unsettled.
The gel contains a Bioactive Decapeptide blend CM2, including alpha-casozepine, and is designed to support relaxation without simply dulling the horse. The 60ml syringe provides three standard 20ml doses for horses weighing under 500kg.
Calming support when your horse needs it
Even normally settled horses can become anxious when their routine changes. Loading into a horsebox, travelling to a show, competing in an unfamiliar venue, spending time on box rest or dealing with changes in surroundings can all contribute to nervous behaviour.
CalmEze EQ 60ml provides nutritional support for horses during these situations and can be administered in advance so that the calming effect has time to develop before the stressful activity begins.
When can CalmEze EQ be useful?
- Travelling and horsebox loading
- Competitions and shows
- Training in unfamiliar surroundings
- Changes in environment
- Box rest
- Generally nervous or excitable horses
- Situations where a horse becomes tense or difficult to settle
- Short-term stressful events
- Multi-day stressful activities when used according to the feeding directions
Sudden changes in behaviour should not automatically be assumed to be anxiety. Pain, illness, tack problems, gastric discomfort or other physical issues can also make a horse appear nervous or difficult. Persistent or unexplained behavioural changes should be assessed by a veterinarian.
Bioactive Decapeptide blend CM2
Each 20ml dose contains a minimum of 1,300mg Bioactive Decapeptide blend CM2.
Kyron describes CM2 as a combination that includes alpha-casozepine. Alpha-casozepine is a milk-derived peptide associated with calming and relaxation responses and forms the key component of the CalmEze EQ formulation.
This makes the paste particularly useful where the aim is to provide nutritional calming support before a known stressful event while allowing the horse to remain responsive and manageable.
Competition use
Kyron states that CalmEze EQ contains no prohibited substances and may be used for competition.
Competition rules can change, so riders competing under a specific federation or discipline should always check the latest competition and medication regulations applicable to their event.
Dosage and directions for use
Administer the paste orally according to the horse’s bodyweight.
| Horse | Dose |
|---|---|
| Foals / Weanlings around 250kg | 10ml per dose |
| Horses under 500kg | 20ml per dose |
| Horses over 500kg | 25ml per dose |
When to give CalmEze EQ 60ml
For an anticipated stressful event, administer the appropriate dose:
- The night before the stressful activity
- Again 1 to 2 hours before the activity
- The dose may be repeated after approximately 5 hours if required
The expected onset of action is approximately 90 minutes.
If the stressful situation continues for longer than one day, the manufacturer advises administering one dose daily for the duration of the activity. The amount can be adjusted according to the individual horse’s response.
How many doses are in one syringe?
A 60ml syringe of CalmEze EQ 60ml provides approximately:
- 6 x 10ml doses for foals or weanlings
- 3 x 20ml doses for horses under 500kg
- 2 full 25ml doses with 10ml remaining for horses over 500kg
This makes the paste particularly convenient for one-off events, travelling days or competition weekends where an easy oral calming option is preferred over a daily powder.
Paste or daily calming powder?
The 60ml paste is well suited to occasional or predictable stressful events because it can be administered directly by mouth before the activity.
For horses needing more regular calming support, a daily powder format may be more convenient. Keen Pets also stocks CalmEze Plus EQ Powder Sachets 50g x 30, which can be mixed into the horse’s normal feed for short- or longer-term nutritional calming support.
Product details
- Brand: Kyron
- Product: CalmEze EQ
- Pack size: 60ml syringe
- Species: Horses
- Form: Oral gel / paste
- Key ingredient: Bioactive Decapeptide blend CM2
- CM2 per 20ml: Minimum 1,300mg
- Typical dose for horses under 500kg: 20ml
- Approximate onset: 90 minutes
Other Kyron horse products at Keen Pets
Browse more horse-care products from Kyron at Keen Pets.
For a daily calming powder option, see CalmEze Plus EQ Powder Sachets 50g x 30.
Storage and responsible use
Store the syringe in a cool, dry place and keep it properly closed when not in use. Keep out of reach of children and uninformed persons.
Calming supplements work best alongside sensible handling, training and environmental management. If your horse develops severe, sudden or persistent behavioural changes, consult your veterinarian to rule out an underlying medical or pain-related cause.
Order from Keen Pets
Buy CalmEze EQ 60ml online from Keen Pets with nationwide delivery across South Africa. The convenient oral syringe provides targeted calming support before travelling, competitions and other stressful situations without the fuss of mixing a daily powder.
Pack size: 60ml oral syringe
20ml contains: Minimum 1,300mg Bioactive Decapeptide blend CM2
Suitable for: Horses

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